This Cheesy Ground Beef Biscuit Casserole is a comforting, family-friendly dinner made with seasoned ground beef, tender vegetables, rich tomato sauce, plenty of melted cheddar cheese, and golden, buttery biscuit pieces baked right on top.
It comes together in one skillet and one baking dish, making it an easy weeknight meal when you want something hearty, cheesy, and satisfying without spending hours in the kitchen.
Prep Time: 15 minutes
Cook Time: 25 minutes
Total Time: 40 minutes
Servings: 6–8
Cuisine: American
Method: Oven-Baked
Recipe Overview
| Details | Information |
| Main Ingredient | Ground beef |
| Topping | Refrigerated biscuits |
| Cheese | Sharp cheddar |
| Preparation | Skillet + baking dish |
| Oven Temperature | 375°F (190°C) |
| Baking Time | 18–22 minutes |
| Servings | 6–8 |
Ingredients
For the Ground Beef Base
| Ingredient | Amount |
| Ground beef | 1½ lbs (680 g) |
| Yellow onion, finely diced | 1 medium |
| Red bell pepper, finely diced | 1 small |
| Garlic, minced | 2 cloves |
| Tomato sauce | 1 can (15 oz / 425 g) |
| Tomato paste | 2 tbsp |
| Worcestershire sauce | 1 tbsp |
| Garlic powder | 1 tsp |
| Italian seasoning | 1 tsp |
| Salt | To taste |
| Freshly ground black pepper | To taste |
| Sharp cheddar cheese, shredded | 1½ cups, divided |
For the Biscuit Topping
| Ingredient | Amount |
| Refrigerated biscuit dough | 1 can (16 oz / 454 g) |
| Melted butter | 1 tbsp |
| Garlic powder | ½ tsp |
| Dried parsley | Optional |
Step-by-Step Instructions
1. Preheat the Oven
Preheat your oven to 375°F (190°C).
Lightly grease a 9 × 13-inch baking dish or a deep square casserole dish and set it aside.
2. Brown the Ground Beef
Heat a large skillet over medium-high heat.
Add the ground beef, diced onion, and diced red bell pepper. Cook for approximately 6–8 minutes, breaking the beef apart with a wooden spoon as it cooks.
Continue cooking until the beef is completely browned and the vegetables are tender.
Drain any excess grease from the skillet.
3. Add the Garlic and Seasonings
Reduce the heat to medium-low.
Add the minced garlic and cook for about 1 minute, stirring constantly, until fragrant.
Add the tomato sauce, tomato paste, Worcestershire sauce, garlic powder, Italian seasoning, salt, and black pepper.
Stir everything together until well combined.
4. Simmer the Beef Mixture
Allow the mixture to simmer uncovered for 3–5 minutes, stirring occasionally.
The sauce should become slightly thicker and coat the ground beef nicely.
Taste and adjust the salt and pepper if needed.
5. Add the Cheese
Remove the skillet from the heat.
Stir 1 cup of shredded cheddar cheese into the hot beef mixture.
Continue stirring until the cheese melts and the filling becomes creamy and cheesy.
6. Transfer to the Baking Dish
Pour the cheesy ground beef mixture into the prepared baking dish.
Spread it evenly from edge to edge.
7. Prepare the Biscuits
Open the refrigerated biscuit dough.
Separate the biscuits and cut each biscuit into 4 smaller pieces. For smaller, bite-sized pieces, you can cut each biscuit into 6 pieces.
8. Add the Biscuit Topping
Arrange the biscuit pieces evenly over the hot beef mixture.
Try to leave a little space between the pieces so the biscuits can cook and brown properly.
Brush the tops with melted butter.
Sprinkle lightly with garlic powder and dried parsley if desired.
9. Bake
Place the casserole in the preheated oven.
Bake uncovered for 18–22 minutes, or until the biscuit pieces are fully cooked in the center and golden brown on top.
If the biscuits begin browning too quickly before they are cooked through, loosely cover the casserole with foil for the remaining baking time.
10. Add the Remaining Cheese
During the last 3 minutes of baking, sprinkle the remaining ½ cup of shredded cheddar cheese over the biscuits.
Return the casserole to the oven and bake until the cheese is melted, bubbly, and golden in spots.
11. Rest and Serve
Remove the casserole from the oven and allow it to rest for approximately 5 minutes before serving.
This gives the cheesy beef filling a chance to settle slightly and makes serving easier.
Serve warm with your favorite side dishes.
Best Tips
Use 80/20 ground beef for a richer and juicier filling. Leaner ground beef can also be used if you prefer a lighter casserole.
Don’t skip draining excess grease after browning the beef. This helps prevent the finished casserole from becoming greasy.
Keep the biscuit pieces relatively small so they have enough time to cook through while the casserole bakes.
Avoid overcrowding the biscuit pieces. A little space between them allows heat to circulate and helps the biscuits become golden and fluffy.
For extra cheesy flavor, use freshly shredded sharp cheddar cheese. It melts beautifully and gives the casserole a stronger cheese flavor.
Let the casserole rest for about 5 minutes before serving so the filling isn’t too loose.
Best Ingredient Options
Ground beef works especially well in this casserole, but you can use another ground meat if desired.
Sharp cheddar gives the strongest cheesy flavor, while mild cheddar creates a softer, creamier taste.
You can also combine cheddar with Monterey Jack, Colby Jack, or mozzarella for a different cheese profile.
For more vegetables, add diced mushrooms, corn, spinach, or zucchini to the beef mixture.
If you enjoy a little heat, add crushed red pepper flakes, diced jalapeño, or a pinch of cayenne pepper.
Recipe Variations
Extra Cheesy Beef Biscuit Casserole
For an especially cheesy version, add another ½ cup of shredded cheese to the beef filling and sprinkle additional cheese over the biscuits during the final minutes of baking.
Spicy Beef Biscuit Casserole
Add ½ teaspoon of crushed red pepper flakes and a finely diced jalapeño to the beef mixture for a spicy kick.
Vegetable Beef Biscuit Casserole
Add diced mushrooms, corn, peas, or zucchini along with the bell pepper for a more vegetable-packed meal.
Garlic Herb Biscuit Casserole
Mix melted butter with garlic powder, dried parsley, Italian seasoning, and a small pinch of Parmesan cheese before brushing it over the biscuits.
What to Serve With It
Serve this casserole with a simple green salad for a fresh contrast to the rich beef and cheese.
Steamed broccoli, roasted green beans, or a vegetable medley also make excellent side dishes.
For a heartier meal, serve it with roasted potatoes or a light soup.
Make-Ahead Instructions
You can prepare the ground beef filling several hours ahead of time.
Cook the beef mixture, stir in the cheese, and transfer it to the baking dish. Allow it to cool, cover it, and refrigerate.
When you’re ready to bake, allow the chilled filling to sit at room temperature for a short time while you prepare the biscuit topping.
Add the biscuit pieces just before baking for the best texture.
Storage
Allow leftover casserole to cool before transferring it to an airtight container.
Store in the refrigerator for up to 3–4 days.
The biscuit topping will soften slightly during refrigeration, but the casserole will still be delicious when reheated.
Reheating
For the best texture, reheat individual portions in a 350°F (175°C) oven until heated through.
You can also use a microwave for convenience. Heat individual servings in short intervals until hot.
An oven or toaster oven will help the biscuit topping regain some of its texture.
Freezing
The cooked beef filling can be frozen, but the biscuit topping may become softer after thawing.
For best results, freeze the beef mixture separately and prepare fresh biscuits when you’re ready to assemble and bake the casserole.
If freezing leftovers, place them in an airtight freezer-safe container and use within approximately 2–3 months for best quality.
Common Mistakes to Avoid
Don’t add the biscuit pieces before the beef mixture has been properly thickened. An overly watery filling can make the biscuit bottoms soggy.
Don’t make the biscuit pieces too large because the centers may remain undercooked while the tops become overly brown.
Don’t cover the casserole during the entire baking process because the biscuits need direct heat to become golden and crisp.
Don’t skip the resting time after baking. Allowing the casserole to sit for a few minutes makes it easier to serve.
Nutrition Estimate
Approximate values per serving, depending on portion size and specific ingredients used:
| Nutrient | Estimated Amount |
| Calories | 520–600 kcal |
| Protein | 27–32 g |
| Carbohydrates | 35–42 g |
| Fat | 29–35 g |
| Saturated Fat | 12–16 g |
| Fiber | 2–3 g |
| Sugar | 5–7 g |
| Sodium | 900–1,150 mg |
Frequently Asked Questions
Can I use homemade biscuits?
Yes. Homemade biscuit dough works very well. Cut the dough into small pieces and arrange them over the beef mixture before baking.
Can I use lean ground beef?
Yes. Lean ground beef works perfectly. Since it contains less fat, you may need a small amount of olive oil when cooking the vegetables if the skillet becomes too dry.
Can I prepare this casserole ahead of time?
Yes. The beef filling can be prepared ahead and refrigerated. Add the biscuit topping shortly before baking for the best results.
Why are my biscuits not cooked underneath?
The beef mixture may contain too much liquid, or the biscuit pieces may be too large or packed too closely together. Make sure the sauce is slightly thick before adding the biscuits.
Can I add more cheese?
Absolutely. If you love a very cheesy casserole, add another ½ cup of cheddar or use a combination of cheddar and Monterey Jack.
How do I know when the biscuits are done?
The biscuits should be golden brown on top and fully cooked through in the center. If you’re unsure, carefully check one of the larger biscuit pieces in the middle of the casserole.
Final Thoughts
This Cheesy Ground Beef Biscuit Casserole is the kind of easy comfort food that makes a satisfying family dinner with minimal effort. The savory tomato-seasoned beef filling, melted cheddar cheese, and golden garlic-butter biscuits come together in one hearty casserole.
It’s simple enough for a busy weeknight, customizable with your favorite vegetables and cheeses, and especially delicious served straight from the oven while everything is warm, bubbly, and cheesy. 🥩🧀🥘